Health for a Lifetime

The Good And Bad Cholesterol

Three Angels Broadcasting Network

Program transcript

Participants: Don Mackintosh, Kevin Bryant

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Series Code: HFAL

Program Code: HFAL000039


00:51 Hello and welcome to "Health for a Lifetime"
00:54 I'm Don Macintosh, your host, and today we're joined by
00:59 Dr. Kevin Bryant, from Wichita, Kansas
01:01 Thank you, Dr. Bryant, for being here! Good to be here.
01:04 One of the things you do as a family practice physician
01:08 is deal with lots of people when they receive lab tests.
01:12 And I understand you're involved in a program in the
01:14 community that looks at really heart disease.
01:19 Right, I have the pleasure of being involved in a community
01:23 outreach educational program
01:25 called: "Coronary Health Improvement Project"
01:28 dealing specifically with the risk factors that promote,
01:34 and cause heart disease.
01:35 How many people have you had
01:36 go through that program thus far?
01:38 We have approximately 600 in our community have gone through.
01:41 And do you have any followup for them once they...
01:43 How long is the program, and then do you have any followup?
01:46 The program lasts for 30 days.
01:48 It's a pretty intensive program.
01:50 And then on a monthly basis, we follow up continuing to
01:54 check their lipid levels, their blood cholesterol levels.
01:59 Cholesterol.
02:00 Do you see big changes? Are people happy with that?
02:04 Dramatic changes can take place in 30 days.
02:08 And, it's rewarding to me as a
02:10 physician to see people make those changes.
02:13 How many times do you do that a year?
02:14 We do it about twice a year now.
02:17 Well maybe some of the folks that are watching today
02:20 don't have the privilege of being in a program like that...
02:23 But let's say they've gone to the hospital,
02:27 or maybe seeing their physician, and they've heard a lot about
02:29 cholesterol.
02:30 Today, really, we're going to talk about how to tell
02:33 the difference between good and bad cholesterol,
02:35 and would it be fair to say that today it's going to be like
02:39 they've just gotten their lab tests back,
02:41 and this would be a good time for them to maybe get out
02:43 those numbers, so that they could learn about how to
02:46 look at those and find out what's happening.
02:48 Yeah, this program today is really designed to try and help
02:52 people understand what the numbers mean
02:54 when they get those reports back from their doctor.
02:57 Okay, so if you're watching today, and you had some
03:01 lab tests that you've had done, maybe cholesterol...
03:04 Run and get those tests, turn up the set,
03:09 and you can hear what's happening...
03:10 But go get those numbers because I think you'll
03:12 really find some things that can help you.
03:15 One thing that kind of intrigues me about the title of
03:18 today's show... You're saying that there is
03:20 GOOD cholesterol and that there is BAD cholesterol,
03:23 I don't know which you want to talk about first,
03:25 but what does that mean?
03:26 Well yeah, I think a lot of people, their impression
03:31 when they hear the word "cholesterol," that it's bad.
03:34 But there's actually good and bad cholesterol,
03:37 and we're going to try and explain that today.
03:40 And the first thing that I find most people
03:42 are confused about is...
03:44 They get a report back and it has cholesterol on it,
03:49 triglycerides, and many people are confused about even those
03:54 terms... thinking that their triglycerides and cholesterol
03:59 are the same thing, when in reality they are
04:01 2 different completely separate
04:04 chemical compounds in our body...
04:06 And so, we have to recognize there's
04:09 cholesterol and then triglycerides.
04:12 Cholesterol, if we had a lump of it here in your hand,
04:15 is kind of a waxy substance,
04:19 as where triglycerides is just a big name for OIL or FAT...
04:24 And so your vegetable oils, your margarine, your butter,
04:28 those are triglycerides.
04:31 And because both the triglycerides and cholesterol
04:35 are waxy or oily, they don't mix with water.
04:40 Oil and water doesn't mix.
04:42 Well that's true in our body.
04:43 Those substances, cholesterol and triglycerides,
04:47 in the bloodstream would not mix.
04:50 So they are 2 different things in other words.
04:53 Two different things, and because of the
04:56 chemical structure, they don't mix with water in the
05:00 serum in our blood.
05:01 So our body has a way to carry those 2 chemicals
05:06 around in the bloodstream produce protein molecules
05:11 that carry the cholesterol.
05:15 They're like little trucks in our bloodstream,
05:18 if you want to think of them that way...
05:19 that are carrying cholesterol and triglyceride around because
05:24 otherwise they would not mix in the bloodstream,
05:27 so they're carried by those.
05:29 And those protein molecules
05:32 are divided into different categories,
05:37 and, as you can see here, they are divided roughly into 3...
05:41 Actually there's, I think, 18 or 19 fractions or different
05:46 We're giving us the 3 main ones that you're going to see
05:49 on a lab result.
05:50 The first one is "LDL" and we're going to talk
05:53 in more detail about these,
05:55 but LDL has become known as BAD cholesterol.
06:00 "Lousy" density lipoprotein,
06:04 and lipoprotein is the name for the protein.
06:07 It just means "lipo" is fat, and then protein.
06:10 So it's the fat-protein combination.
06:14 So LDL is considered bad because it tends to carry cholesterol
06:20 to the wall of the artery.
06:22 It makes it fat; makes it clogged up.
06:25 That's the one that is kind of a culprit and we'll look at that
06:30 The good cholesterol is called "HDL"
06:34 So when you look at a lab result you want to look for
06:36 LDL - bad HDL is the good cholesterol.
06:41 "Happy" density lipo. Lousy and happy... all right
06:45 And it does kind of the opposite.
06:47 In a simplistic way, it's doing the opposite of the
06:51 bad cholesterol; it's trying to take cholesterol
06:54 out of the wall of the artery where these plaques are
06:57 in the artery, and take them back to the liver.
07:02 So the lousy dumps it off in the artery;
07:05 the happy says, "I'm not happy with that and takes it away. "
07:08 In a simplistic way that's the way to look at it.
07:11 And then, another one called VLDL is a protein that carries
07:16 a lot of the triglycerides or fat around in the bloodstream
07:19 Which are totally different than
07:21 cholesterol, what you've told us Exactly, completely different.
07:25 Now, if we look more specifically at the
07:31 low-density lipoprotein, the LDL what we called bad cholesterol,
07:37 we talk about it carrying cholesterol around.
07:42 Now, in essence, the cholesterol is the same cholesterol
07:46 whether it's in an LDL, or an HDL protein molecule.
07:52 But it's the protein molecule that makes the difference
07:56 where that cholesterol is going.
07:57 Is it going to the wall of the artery or out of the
08:00 wall of the artery back to the liver to be disposed of?
08:04 And that protein molecule is LDL?... is LDL or HDL
08:10 Now as time has gone on and research has been done
08:16 on this LDL molecule, we've discovered that
08:20 by itself, pure cholesterol does not damage
08:26 the wall of the artery or cause a problem.
08:29 It's only when that cholesterol and that protein becomes
08:35 oxidized, either exposed to air in the animal products
08:42 where the cholesterol may have
08:43 been if you're eating animal products...
08:47 or if sometimes in the body's metabolism
08:53 free radicals are produced that oxidize the cholesterol
08:58 and the LDL protein.
09:00 When that happens, the body then begins to recognize
09:04 this as actually as though it's a foreign body...
09:08 almost like a bacteria, an enemy.
09:09 And so part of the immune-fighting cells
09:15 particularly the ones called macrophages, actually begin
09:19 to engulf those particles...
09:22 ...the LDL particles in the wall of the artery in an attempt to
09:27 ...just like if it was an enemy.
09:30 Let me see if I have this straight...
09:32 So LDL, the lousy density lipoproteins,
09:39 are those that have been exposed to air either outside
09:41 the body, so food would be like any dairy products,
09:46 or anything that have been exposed to air,
09:49 or INSIDE the body that even
09:51 happens inside your body without your doing anything,
09:54 and so the point of this really is there are ways
10:01 trying to prevent that from taking place...
10:04 because that's the important point.
10:06 Just having the cholesterol, the LDL there,
10:09 is not going to damage the wall
10:13 of the artery until it becomes oxidized.
10:16 So if we can prevent that oxidation from taking place...
10:20 Either on the outside... either by not eating those
10:23 animal products because they have oxidized cholesterol
10:28 in them, which is going to be harmful to your vascular system,
10:34 or, and this is where our what we call antioxidants,
10:39 vitamins that are antioxidants are very important.
10:44 So ANTIOXIDATION... anti what the air is doing.
10:48 Right. They, in other words, prevent that process
10:52 from taking place.
10:53 So we know that even if we have 2 different groups of
10:59 people that have the same cholesterol levels;
11:03 one group is eating those things that are high in antioxidants
11:08 which are fruits and vegetables.
11:10 The other group was eating low; they don't have as many
11:14 antioxidants.
11:16 The group that is NOT eating the antioxidants in their food
11:21 are going to be at GREATER risk for heart disease,
11:24 even though their cholesterol levels are the same.
11:26 So they got their lab sheet out at home and they're
11:28 looking at it and it says my total cholesterol,
11:30 let's say it says it's 200, that's not enough to look at.
11:34 They've got to look at, what does it say concerning LDL;
11:37 what does it say concerning HDL?
11:39 We've TALKED about the LDL, what's a good number for LDL?
11:41 Okay right... well, LDL numbers, and this may be somewhat
11:46 different from if you have your lab value there
11:48 in front of you, the labs frequently put a reference
11:52 number, what's normal... and then they have a little
11:55 star that comes up if it's abnormal. Right
11:57 And, we're finding now that if that number is below 90,
12:04 that that's the ideal range.
12:08 There may be what's normal in America,
12:10 but we want to be ideal, and so 90 or below is really
12:14 the ideal range that we want to be in.
12:18 Now usually in those normal sheets,
12:20 what do they normally say in your lipid area?
12:25 What do they say is normal in your area?
12:28 Normally in America, below 130 is considered normal.
12:35 So that's quite a bit different than 90.
12:37 Right, we still find a lot of people with heart disease
12:40 with the LDL numbers between 100 and 130.
12:45 Should someone panic if their number says 120 or 30 today?
12:50 Not necessarily, I think that's a call to that person
12:53 to find out how do I lower that number... how do I get that down
12:59 And I think you've mentioned, sort of how to do that...
13:03 stay away from oxidized foods.
13:06 Well, right... because one of the main ways that LDL is
13:12 is raised in the bloodstream is by either eating cholesterol,
13:18 animal products that have cholesterol,
13:20 OR foods that are high in fat, particularly what are called
13:25 saturated fats.
13:27 Primarily those fats that are found in the animal products...
13:31 they are what cause the body to produce more of
13:35 this LDL protein to carry that cholesterol around.
13:40 We've been talking with Dr. Kevin Bryant.
13:43 He is a doctor in family practice.
13:48 He focuses on heart disease and helps people understand
13:51 their lab tests and their values.
13:53 We've talked about cholesterol, the bad type of cholesterol...
13:56 And when we come back, we're going to look further at a good
14:00 type of cholesterol... HDL
14:03 We hope that you join us.
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15:27 Welcome back, we've been talking with Dr. Kevin Bryant
15:32 from Wichita, Kansas,
15:33 He's a specialist in family practice...
15:36 And today, we're talking about heart disease.
15:38 And really, what we've been talking about is lab tests,
15:43 cholesterol... how can we tell whether or not we've had a good
15:46 result or not.
15:48 If you've just joined us, and you recently had a lab test,
15:51 and you know where it is,
15:53 why don't you run and go get that lab test and have it there
15:56 as you're listening to Dr. Bryant.
15:57 On the first part of the program we talked about
16:00 low-density lipoprotein, did I say that right?
16:03 You've got it down.
16:04 "Lousy" cholesterol because what it does is
16:07 it puts, you see if I'm right,
16:09 I'm seeing if you're a good teacher...
16:11 It puts the cholesterol right in the walls of our arteries
16:15 and thickens them up, and that can cause real problems.
16:18 So we don't want that to happen.
16:20 And so we explained that LDL, but now we want some good news.
16:25 We've had the bad news; do you have some
16:27 good news for us today, doctor?
16:29 Obviously, we've talked about the bad cholesterol,
16:33 now we want to look at the flip side, the good cholesterol,
16:36 and again, it's the same cholesterol,
16:38 it's just a different carrier truck that we've talked about;
16:43 the protein molecule is different.
16:45 So now, the good cholesterol is carried by an HDL protein,
16:51 so when you look at your lab result,
16:53 the HDL is good cholesterol.
16:57 Happy! "Happy" density lipoprotein is
17:01 one way of looking at it.
17:08 Now, the function that HDL has is opposite to the LDL.
17:12 It's reversing... it's taking cholesterol out of that wall
17:17 of the artery back to the heart.
17:19 It's almost like there's this tug-of-war between these 2
17:23 protein molecules.
17:25 Bad cholesterol protein LDL
17:28 putting it into the wall of the artery...
17:30 HDL trying to take it back out.
17:33 And so there's a balance here going on between the 2.
17:37 And that's why you want the bad cholesterol portion, the LDL
17:42 to be as low as possible.
17:44 You want the good cholesterol to be high.
17:49 So is there ever anyone that has a lab test
17:54 where there's no LDL?
17:57 Where there's no LDL? No
18:01 You would probably be "dead" if you had none.
18:06 Okay, so you'd have to have some.
18:08 Is there ANYTHING good about LDL that we have to have some?
18:12 Well actually, I mean, it is one of the carriers that carries
18:16 cholesterol; all of our cells NEED cholesterol.
18:19 So the arteries... they need cholesterol, the actual wall,
18:25 but the problem in America is they get too much.
18:27 They get too much... right, begins to clog the system up.
18:31 So, we can kind of tip the scale as who's going to win this
18:35 tug-of-war by what we eat or don't eat,
18:37 all those different kinds of things. Right
18:39 And now what we eat, affects
18:41 the LDL, the bad cholesterol.
18:44 What affects the HDL and raises that because we want more
18:49 of that... to take the cholesterol back out
18:51 of the wall of the artery; try and open the arteries up.
18:54 There are 3 main things that affect that.
18:57 Let us know those 3 things.
18:58 What are those 3 things, because we want to happy, happy, happy!
19:02 Well the first is our weight.
19:06 If we're overweight, obesity LOWERS the HDL, decreases it...
19:14 So as a person loses weight, over time, that will help
19:19 the HDL level rise.
19:22 And it doesn't happen overnight,
19:24 it happens usually in several months, sometimes up to a year.
19:30 As that weight is coming down, that the HDL number will go up.
19:34 We find, in this program that I'm involved with,
19:37 that in 30 days, the LDL, the bad cholesterol number
19:41 can come down dramatically,
19:43 but it may take months to a year for the HDL level to rise.
19:48 Oh, so in other words, if the LDL is going down,
19:50 you've started some good lifestyle things,
19:53 you need to wait a while for the HDL.
19:56 Yeah, don't expect that one to change overnight.
19:59 So weight is one issue.
20:01 Smoking is another issue.
20:03 Smoking also drives the HDL level down. How does that work?
20:08 Not exactly sure how that connection is there;
20:12 we've just seen that relationship that individuals
20:16 smoking have lower HDL levels and when they quit,
20:20 over time, that level rises again.
20:22 So losing weight, stopping smoking,
20:25 and then the 3rd, probably one of the most powerful ways
20:28 to raise the HDL level is exercise.
20:32 And it's really what we call dose-dependent relationship
20:37 ...The more you exercise,
20:39 the more effect it has on raising the HDL level.
20:43 Let me ask you a question about that...
20:45 Can you lose weight without exercising?
20:47 You can lose weight...
20:51 Just by caloric or by what you take in...
20:53 You could lose weight that way.
20:55 So exercise really should be looked at as something
20:58 different than losing weight.
21:00 I mean they may be related, but what you're saying
21:03 is that it's not enough to just lose weight by not
21:05 eating as much food; you need to be out there
21:08 if possible putting some pep in your step,
21:11 and spunk in your trunk just moving it.
21:14 Yeah, the exercise is what's going to help you
21:15 maintain that weight loss...
21:19 What if I can't walk?
21:21 What kind of exercise do I do then?
21:23 Maybe able to swim. Okay
21:26 Cycle. Water aquatics or something like that. Right
21:29 Anything to raise that HDL.
21:33 So lose weight, stop smoking, and exercise. Right
21:39 And the number that we're shooting for is above 40;
21:45 somewhere in the range of 40 or greater.
21:49 In fact, the higher you can get that number, the better.
21:53 So, let me just review a a little bit;
21:55 maybe someone just was joining us.
21:57 The LDL needs to be 90 or below.
22:02 The HDL, if possible, needs to be 40 or above. Right
22:09 Okay, now those are looking at the cholesterol issues.
22:15 Now, we're going to turn and focus on triglyceride.
22:19 What you've said is different,
22:20 completely different than cholesterol.
22:22 It's a different molecule.
22:23 It might be on the same sheet of paper,
22:25 you're looking at your lab tests, but it's different.
22:27 Right, and for a number of years, we weren't really sure
22:31 if triglycerides really affected your risk for heart disease...
22:36 We now know that it does.
22:39 Now triglycerides, again, are carried by what's called...
22:43 "VLDL" another protein molecule that's carrying
22:47 the triglycerides, so when you look at your lab tests
22:50 you'll look down sometimes and see "VLDL"
22:53 and that's mainly carrying triglycerides,
22:56 and also some of the cholesterol is carried in that,
22:59 and we'll talk about that.
23:01 But we know that if that value for triglyceride levels is
23:07 greater than 150, then the risk for heart disease
23:12 begins to go up...
23:13 And this is independent of what your cholesterol level is.
23:17 So, wait a minute, the triglyceride level, if it's
23:20 greater than 150...
23:22 Over 150, the risk for heart disease begins to go up
23:27 irregardless of what your cholesterol level might be.
23:31 So just standing alone looking at it...
23:33 You know, I've seen some tests, even my own lab tests
23:37 where the triglycerides one day seems to be real high,
23:40 the next day seems to be real LOW...
23:42 Is it, is it? Well, and this is how the blood
23:46 is drawn is very important.
23:48 To get an accurate measure of the triglyceride level,
23:51 you have to be fasting for at least 12 hours.
23:54 Oh, I see... So if someone is looking at a lab test today
23:58 and they just went in and got it drawn,
24:00 they went into the emergency room or something,
24:02 and they haven't been fasting,
24:03 then that's really not even something to look at. Right
24:06 Can't judge then.
24:07 Now there are a number of things that are involved in
24:11 raising and lowering those triglyceride levels,
24:15 and our illustration goes through a number of the
24:18 major determinates for triglyceride levels.
24:22 Excess weight, again, the weight RAISES
24:27 triglyceride levels.
24:29 Since triglycerides are fat molecules,
24:32 it only stands to reason that if you have a high fat intake,
24:36 you're going to have high fat levels in the bloodstream.
24:40 STRESS is an interesting one.
24:43 The higher the stress level, because of some of the
24:47 hormones that are produced from the stress reaction,
24:51 they stimulate the body to release fat and raises the
24:56 fat levels in the bloodstream.
24:58 I see, and then the other ones were the same...
25:00 lack of exercise, high fat intake and exercise. Right
25:03 And STRESS as well, so wow...
25:07 And sometimes diet areas... the high carbohydrate intake,
25:14 high sugar intake, alcohol intake can raise
25:18 the triglycerides.
25:20 Now, we've talked about the bad cholesterol,
25:27 good cholesterol, the triglyceride, VLDL.
25:33 If you add all those up, LDL, HDL, and the VLDL,
25:40 all those numbers, VLDL has to be divided by 5,
25:44 add those all up and that will give you your total cholesterol.
25:48 Okay so, say I have an LDL of 100,
25:51 I have an HDL of 50, and then I have an VLDL say of 200,
25:57 divided by 5 is 40.
25:59 That will give you your total cholesterol.
26:02 So your total cholesterol is carried in the blood by
26:05 these different protein molecules.
26:07 That's what that number means. Right.
26:08 LDL, HDL, VLDL divided by 5, all added together. Right
26:13 And that total cholesterol number really even though
26:19 some of the labs still report it as normal below 200,
26:24 and when we look around the world,
26:26 we find that populations that have total cholesterol levels
26:31 below 150 on the average, we don't find heart disease,
26:35 and so many of the researchers in this field are pushing
26:41 for a lower total cholesterol level.
26:43 Doctor, we have 30 seconds...
26:45 We've talked about...
26:46 I want to give you 30 seconds for this little answer.
26:49 We've talked about LDL.. "lousy"
26:52 We've talked about how to get that out of your system.
26:55 We've talked about HDL.
26:56 We've talked about how that's "happy"...
26:58 we want to elevate that.
27:00 And what are some... just summarizing some
27:03 things that people can do to have a good cholesterol?
27:07 Obviously, looking at diet.
27:11 Diet is going to be the foundation #1.
27:13 Okay, diet... what else?
27:15 #2 is going to be the exercise... Exercise
27:18 #3... is going to be looking at their weight... losing weight
27:22 And then you said.. #4... Smoking
27:25 Smoking and then maybe stress.
27:27 And stress.
27:28 Thank you so much for being with us, Dr. Bryant.
27:31 We've been talking with Dr. Kevin Bryant
27:33 from Wichita, Kansas.
27:35 We've learned that there's good cholesterol,
27:37 we've learned that there's bad cholesterol.
27:39 We've learned how to really
27:41 have a good cholesterol and what to do.
27:43 We hope that what you've learned today will be a help to you,
27:46 but not only you, maybe others that you know.
27:50 And as a result of today's program, that you will have
27:54 health that lasts for a lifetime!


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Revised 2014-12-17