Health for a Lifetime

Physiology Of Menopause

Three Angels Broadcasting Network

Program transcript

Participants: Eric Shadle, Don Mackintosh

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Series Code: HFAL

Program Code: HFAL000112


00:51 Hello and welcome to "Health for a Lifetime"
00:53 I'm your host Don Mackintosh
00:55 We're glad you've joined us today.
00:56 We're going to be talking about women's health issues today,
00:59 and joining us to talk about this vital subject
01:02 is Dr. Eric Shadle
01:03 Welcome Dr. Shadle. Thank you
01:06 We're glad that you're with us.
01:07 Now, you know, you've been in obstetrics and gynecology,
01:10 I guess is the subspecialty that you're in,
01:12 for about what, 15-16 years now. Yes, that's right
01:16 And so you've seen a lot of things that deal with
01:19 women's health issues, but today we're going to be
01:20 talking about menopause. Yes
01:23 And, is this a big problem, a lot of people
01:25 coming to see you about this?
01:26 Actually, it's probably one of the
01:28 bigger problems that I'm consulted for.
01:32 Of course, all women, if they live long enough,
01:35 go through the menopause, and so it's something that
01:39 is a big issue for most women.
01:41 What exactly is menopause,
01:43 and what are the stages involved in that.
01:45 Well there are at least 2 stages
01:47 that I'd want to talk about today...
01:49 One, is the perimenopause, that's the first stage,
01:52 and that's the time when the ovaries function is decreasing;
01:57 it's making less and less estrogen,
02:00 and there could be a variety of
02:01 symptoms associated with that.
02:03 And then there's the menopause itself which is when the
02:06 ovaries stop functioning altogether.
02:08 So really, that's what the word "meno-pause" means
02:11 a pausing or cessation maybe of the menses or the period.
02:16 Yeah, that's right... And I think you have a graphic
02:18 about this that kind of gives us the details and there it is.
02:22 It talks a little bit about the definitions.
02:24 The perimenopause actually the average age is 47,
02:30 though it can last for several years.
02:32 I think the graphic talks about that it can last for 2-6 years,
02:37 and it may not occur at all, though sometimes the ovaries
02:42 just stop functioning until you have regular periods
02:45 right up into the menopause...
02:47 And then the average age for menopause is age 51,
02:51 and 90% of women actually go through the menopause by age 55,
02:56 so it's rare to go beyond the age of 55.
03:00 So then in making the diagnosis, I mean...
03:02 the age factors into it and other different things...
03:04 What kind of things do you say - Hey, this is what's happening...
03:09 Well the most common way to make a diagnosis
03:11 of the menopause is simply by history.
03:13 The clinical history - when a woman comes in and says,
03:17 "Well, I haven't had period for 6 months or for a year"
03:20 ...then I know that she is menopausal;
03:24 her ovaries aren't functioning.
03:27 But we can confirm that with laboratory tests.
03:29 There is a laboratory test, something called "FSH"
03:33 That's "follicle stimulating hormone"
03:34 That's a hormone made in the pituitary gland that
03:38 controls ovarian function and it is secreted by the
03:42 pituitary gland to tell the ovary... what to do and when.
03:46 That's right... And when the ovary stops functioning,
03:49 the pituitary glad goes into overdrive,
03:52 and keeps reminding the ovary to function
03:56 even though it won't do it at that time because it's
03:59 physiologically time for the ovary to stop functioning.
04:02 So it goes up - in other words,
04:05 but there's no response from the ovary. That's right
04:07 And you can see that in the blood and you say,
04:09 "Okay, this is what's happening, so you're at that stage
04:12 and it's okay" That's right - it's okay
04:15 But interestingly enough, that FSH does stay high
04:19 throughout a woman's life.
04:21 So, there's something in the pituitary gland
04:25 that keeps secreting that FSH -
04:27 even though it doesn't do anything,
04:30 and so some of us in the field believe that FSH probably has
04:36 another function because I don't think that
04:41 God would have made a woman's pituitary gland in a way
04:46 that wouldn't down-regulate
04:48 once it realized the ovary was not functioning.
04:51 I mean you're just trying to figure out what that is,
04:53 and don't know exactly... Yeah that's right - not exactly
04:55 Now you have down here something about
04:56 perimenopausal transition.
04:58 It sounds like a big word but I suppose it's talking about
05:01 the transition from having the regular periods to none at all.
05:05 Is that what that means? Yes, exactly,
05:07 and that can be a difficult time for many women...
05:12 And in fact, menopausal symptoms that most women talk about
05:17 are actually in this transition time,
05:19 this perimenopausal transition that can last for years,
05:23 and can have a variety of symptoms.
05:26 Their vaginal bleeding can be very unpredictable.
05:30 It can be heavy or they may miss periods,
05:33 and it could be very light and it all has to do with the
05:38 fluctuation in estrogen levels that's occurring in the ovary.
05:43 So it really has some things that affect how someone feels
05:46 emotionally and this and that. Yes
05:49 I've never been through that myself and neither has my wife,
05:53 you know, we're not quite to that stage.
05:57 These kind of things though I certainly have heard about,
06:00 and we certainly know about.
06:02 So what are some real symptoms then of the perimenopausal time?
06:05 Well, we have symptoms of the perimenopause which...
06:09 Like up here in the graphics like hot flashes... That's right
06:12 Hot flashes, the irregular periods that I talked about -
06:14 that can be periods that a woman may miss periods,
06:22 or she may have frequent periods.
06:24 It can include mood swings, fluid retention which can
06:29 be one of the symptoms of fluid retention may be bloating;
06:32 memory problems, headaches -
06:34 Those are some of the perimenopausal symptoms
06:38 that we see and we... So when people come in
06:41 and they have that, how do you help them,
06:44 for instance, can you help someone with hot flashes?
06:47 Yes, we can help women with hot flashes.
06:50 I guess you're going to talk about that a little bit later...
06:53 And with all these things, there are things that you do
06:55 that help them. Right
06:57 And depending on the level...
06:59 There are specific symptoms and we can either
07:04 look at it as treating each individual symptom
07:07 or try to treat the underlying cause which many of those
07:12 may be an estrogen deficiency,
07:15 but that's another issue that maybe we can get to
07:20 a little bit later.
07:21 And really, you know, let's say we're talking in a
07:24 Western medical model... That's right
07:26 We're talking in America and we're talking Western medicine,
07:31 but later on sometime, we can talk about
07:34 what you would do if these things started happening
07:36 in your country or if you're in a place
07:37 where you can't go see someone like you.
07:40 What does that mean?
07:43 That's perimenopause, the hot flashes,
07:45 and all those things we talked about.
07:47 What are the symptoms then in menopause?
07:48 Well the first symptom I would describe would be
07:52 vaginal dryness.
07:53 There can also be symptoms such as skin changes,
07:57 urinary problems, decreased sexual drive or libido
08:02 is described as well as some of the symptoms of menopause.
08:06 Skin changes, what do you mean by that?
08:07 It can be skin dryness, wrinkling
08:10 can occur more and more.
08:12 Is this because there is not as much estrogen?
08:14 It is thought that estrogen certainly plays a role
08:18 in that because it increases the elasticity of the tissue
08:22 and so as estrogen is withdrawn,
08:25 there is less elasticity in this dryer skin and more wrinkling.
08:29 So these kind of things though can really cause -
08:32 what would you say - maybe disruptions or
08:36 fluctuations in someone's relationships too
08:39 I mean, these are very intimate things we're talking about.
08:41 And do you find yourself talking not just to
08:45 the lady but also the man sometimes in these situations?
08:51 For menopausal symptoms, actually I don't have husbands
08:55 coming in with their wives very often.
08:57 That occurs in other situations in my practice,
09:01 for example, infertility issues, couples that are wanting
09:05 to get pregnant...
09:06 But generally, women in the menopause, of course, are mature
09:12 and they kind of have their own ideas on what
09:18 their issues are and they generally don't bring
09:20 their husbands with them.
09:21 But you're right, it does impact the couple;
09:24 it can impact them greatly.
09:27 So how should a man be reacting at this particular time?
09:30 I mean, I know that's a really open question,
09:32 but are there some pointers that you sometimes -
09:35 you would say? I know this is not on our
09:37 list of things but how should they react;
09:39 just sensitively and... Absolutely
09:42 I think a man needs to understand that there are
09:46 changes that occur in a woman that are physiologic.
09:49 There are changes that occur because she's going
09:52 through hormonal fluctuations and that has real effects
09:58 on her body.
10:00 It's not imaginary, she's not imagining these things...
10:03 And mood swings could occur that we haven't listed
10:09 on graphics but mood swings certainly can be
10:12 one of the things that women have in the transition
10:15 or even in the menopause.
10:17 So then, what is the timing here of the menopause?
10:21 We've talked about how it comes...
10:23 There is the perimenopause which is physiologically,
10:26 but what more about timing do we need to know about?
10:29 Well, timing is determined... it seems to be predetermined
10:34 in many ways by a programmed loss of the ovarian follicles.
10:38 Those follicles are the eggs that a woman has.
10:44 She has a certain number of eggs in her ovaries,
10:47 and several of them are maturing each month due to
10:52 hormonal stimulation and so several of them are used up
10:57 every single cycle...
11:00 And at a given time, they're all used up more or less,
11:06 and that's when we see the menopause occurring,
11:10 and as I said before, the average age is 51;
11:13 55 is considered to be the upper limits of normal
11:18 of an age to go through the menopause.
11:20 If you smoke does that make a difference?
11:21 Smoking does cause the menopause to come earlier.
11:26 Also if a woman has never had children,
11:28 she could probably expect to go
11:30 through the menopause earlier...
11:32 And maybe that's because for those 9 months of pregnancy,
11:35 there are no eggs being used each month.
11:39 I just was going to ask that so that explains it.
11:41 So let's come back to this issue of hot flashes.
11:44 What exactly is happening
11:45 physiologically there, what's going on?
11:47 Well hot flashes actually occur in about 75% of menopausal women
11:53 It's a very common symptom and we think it's due
11:57 primarily to estrogen deficiency...
12:00 But there can be a variety of causes for hot flashes.
12:04 The first type of causes would be physiologic
12:08 such as the menopause, but other physiologic causes
12:13 would be hot drinks or emotional distress.
12:16 So men can have hot flashes too.
12:18 I bet our viewers didn't realize
12:22 that actually men can have hot flashes.
12:24 So when you mean "hot drinks," something you drink that
12:26 makes you feel hot? That's right
12:28 It can actually cause a response that would cause a flushing
12:33 especially in the chest and the face and the head.
12:36 So I guess if you take some niacin too - some people tell me
12:39 that that will make you have a serious hot flash.
12:42 That's exactly right, a serious hot flash.
12:45 So what about, you have down here also some drugs
12:47 that can make you feel like you have a
12:49 hot flash-type symptom.
12:50 Yes, drugs and under drugs I would include
12:54 not only medications but drugs such as alcohol,
12:57 especially in Asian women alcohol has a big effect.
13:02 There are other medications that may have an effect as well.
13:08 That cause you to just feel like you're flushed and flashed
13:12 and everything like that.
13:13 So you kind of have to work through those.
13:15 It could be menopause but it could be something
13:16 else you're taking... There could be medications
13:18 that we'd have to look at or could be actually diseases.
13:20 One of the most common would be carcinoid syndrome.
13:24 It can be serious... What is carcinoid syndrome?
13:26 It's actually a syndrome where the body starts making
13:31 too much of a certain hormone,
13:33 and it can cause dramatic effects on the heart,
13:37 blood pressure and other effects.
13:40 So hot flashes then could be from something you drink,
13:45 some medication or drugs you're taking,
13:47 and then also various diseases.
13:49 So, if you're having hot flash, basically the bottom line is...
13:52 and you don't know what's causing it,
13:53 or you have any suspicion, they really should
13:55 see somebody like you, is that right? Yes
13:58 Because that can be a real sign of something.
14:00 It can be a sign of something, but we learn something
14:04 in medical school - if you hear hoof beats,
14:06 you generally think of horses not zebras,
14:08 and so we look for the most common.
14:12 So you have a woman who is 51,
14:14 she had her last period 8 months ago and she's having hot flashes
14:20 ...then we know that that's most likely menopausal symptoms.
14:25 It's due to an estrogen deficiency,
14:26 and something that we need to look at.
14:28 What is you're having hot flashes and you're 17?
14:30 Or if you're having hot flashes, and you already
14:33 went through menopause, and now you're 70,
14:35 and you're having those again, that's a different thing.
14:38 That may be a different thing altogether.
14:39 Okay, so that's something that we need...
14:41 When the light goes off in the car,
14:43 you know - that dummy light that says,
14:45 "Hey, you better get it checked out"
14:47 This is that kind of thing. That's right.
14:49 Anything else about hot flashes?
14:50 We don't want to miss anything on that.
14:51 Well, they are caused by, we think what we'd call
14:55 a thermoregulatory dysfunction in the brain.
14:58 The brain actually controls our temperature,
15:05 and there is something there that can reset that,
15:10 and it is sensitive to estrogen,
15:12 that's why we do think that estrogen is a major part in that
15:15 Do we ever get over hot flashes, or will they leave?
15:18 I mean, maybe people just starting that and they say,
15:20 Man, I can't do this anymore... They get over them? Generally
15:24 Hot flashes are self-limited but that self-limiting factor
15:29 can be for 5-6 years, so it's pretty hard to tell
15:31 a woman who has just started hot flashes in the last
15:36 few months - to tell her, "Don't worry about it,
15:38 they'll go away in 6 years"
15:40 because she may have several a day and they can be very
15:44 disturbing to her; they may be embarrassing
15:46 because she may feel like she's red even though she's not,
15:50 and she feels like everybody can
15:52 see her and it can be very distracting to her.
15:56 We're talking with Dr. Eric Shadle
15:58 He is a specialist in women's health issues,
16:01 obstetrics and gynecology.
16:03 We've been talking about some very practical issues today.
16:06 When we come back, we're going to be talking about
16:07 more things that occur with the
16:10 body at or after the time of menopause.
16:12 We hope that you join us when we come back.
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17:27 Welcome back, we've been talking about women's health issues.
17:30 We've been talking about menopause really,
17:32 an exciting subject or a subject that a lot of people deal with.
17:36 We've talked about hot flashes.
17:38 We've talked about when we know we're having that;
17:41 what we should be looking for.
17:43 We've talked about the fact that a hot flash
17:45 at the right time in life is really, what would you say...
17:49 no big deal but it tells us that menopause is occurring,
17:52 but if it's happening at other times,
17:54 we may want to look and see what is really occurring.
17:58 We wanted to talk a little bit more about the health issues
18:03 that occur during or after menopause with ladies that
18:08 maybe they don't occur before that time.
18:10 And one of the things we have down here is about
18:12 urinary problems - talk with us a little bit about that.
18:16 Well, several urinary problems that seem to be directly
18:20 related to an estrogen deficiency.
18:23 The base of the bladder and vaginal tissue have
18:27 a high number of estrogen receptors,
18:30 and when estrogen is not binding to those receptors,
18:35 then we lose elasticity not only in the vagina,
18:40 but in the base of the bladder as well.
18:42 It also, those estrogen receptors, increase the amount
18:48 of glycogen in those cells.
18:50 It helps maintain vaginal pH as well as the pH in the bladder
18:57 and thus it can decrease the number of bladder infections,
19:01 and it can decrease the, what we call, vaginal prolapse
19:07 or symptoms of vaginal relaxation.
19:13 Okay, so after menopause these things then start to occur,
19:16 you have problems with all those things;
19:20 maybe urination, maybe leakage,
19:22 all those different kind of things. That's right
19:24 The leakage - there are 2 main types of urinary leakage
19:29 that we find...
19:30 One is what we call "stress incontinence"
19:32 and that's due to not only that loss of elasticity,
19:39 but it's also due to the fact that there's an angle
19:43 between where the bladder and the urethra join
19:46 and that angle needs to be at the proper angle or
19:52 else there can be - when you cough or any increase in
19:56 intraabdominal pressure will cause a loss of urine.
19:59 So when the elasticity changes, then the angle changes
20:04 and then things that wouldn't have caused that before
20:06 start to cause that. That's right
20:08 The other type of urinary leakage,
20:11 we call "urinary incontinence" would be what we call
20:15 "urge incontinence" and so the bladder as it gets full
20:20 but maybe not as full as it should be to be able to
20:23 cause those symptoms, the woman then has to
20:27 get to the bathroom and go right away;
20:29 otherwise, the urine comes out.
20:31 And these are good things to know because
20:34 I mean, look - you're going through this and you've never
20:37 been able to talk to someone like you,
20:38 and you can understand what's happening.
20:43 You know, are there any other significant medical problems
20:47 that occur after or... you know,
20:50 I guess it would be after menopause?
20:53 Yes, there are 3 main concerns, serious medical concerns
20:59 that we have...
21:06 Well let's talk about those a little bit.
21:08 What about the osteoporosis, why is this a problem?
21:11 It is a huge problem in this country.
21:16 It involves over a million women and it is a problem where
21:23 up to 1 to 5% of bone is lost each year.
21:27 Wow - that's a lot of bone.
21:28 That's a lot of bone and women seem to be losing
21:33 more bone after the menopause or during those years
21:37 after age 50 or so.
21:39 So we have to look at that and that's something that seems to
21:42 accelerate then after our periods stop or after menopause.
21:46 Then what about heart disease?
21:48 Heart disease also increases dramatically after a woman
21:52 goes through menopause.
21:54 Before that time, her incidence of heart disease is
21:59 quite a bit less than men, and then after menopause
22:03 her incidence starts rising rapidly to get to about
22:09 the same level as men.
22:10 So there's some kind of protective element
22:12 that seems to go away.
22:13 That seems to go away - at least that's one of the
22:16 theories that we have that it's easy for us to
22:19 try to draw that conclusion based upon this
22:22 menopausal timeframe.
22:23 And then probably, one of the things that causes the most
22:26 fear in women is when you say "breast cancer" - That's right
22:29 And that seems to occur more after menopause?
22:32 Breast cancer incidence does rise with age whether it's
22:37 due to something in the menopause or whether it's
22:41 just an age-related phenomenon...
22:43 And one could say the same with the others that
22:46 we just talked about - osteoporosis and heart disease
22:49 as well because that may be more of an age-related issue
22:54 though we see a big rise at the menopause making us
22:57 wonder if there's a specific cause related to the menopause.
23:02 I know that this subject of estrogen and heart disease
23:05 is pretty controversial and maybe we'll talk about
23:08 that more some other time, but there seems to be
23:12 a real focusing in on the things that are secreted
23:15 by the body and before menopause and then afterwards
23:18 saying - Hey, this must have something to do with it. Yes
23:21 Okay, let me ask you this question...
23:23 I know you're a Christian physician,
23:25 and you practice not only as a physician but also you've
23:32 done some pastoring as well.
23:35 And this is kind of a philosophical question too,
23:38 I would imagine - Is menopause a natural thing?
23:40 Did God create us to be that way or women to have
23:44 menopause?
23:45 Is it a natural state?
23:46 I believe that menopause is a natural state,
23:49 and we know that in Biblical times, early on,
23:53 we know Sarah must have had concerns about menopause,
23:57 and not being able to have children.
24:00 The child of promise - That's right!
24:01 So it's not something that is new.
24:04 It's not something that we've seen just in the last 100 years.
24:07 I think it's something that's been there
24:10 whether it came as a result of sin is certainly
24:15 open to debate, but it is something that every woman
24:20 goes through.
24:22 It's hard for me to define something as a disease
24:27 if 100% of the population has it.
24:30 We generally think of a disease as something that is different;
24:33 something that has a specific cause, and when you have
24:39 menopause, this is a condition that every woman goes through.
24:43 So really, the way you relate to patients then is not a disease
24:47 model that says - This is something wrong with you;
24:49 we're going to fix it, but this is something that...
24:53 This is something that's natural.
24:54 This is something that every woman goes through,
24:57 and we need to individualize as to what type of
25:01 treatment would be appropriate;
25:04 what is the best for a particular woman based upon
25:07 her own specific symptoms as well as
25:11 her own lifestyle patterns;
25:13 what type of diet is she eating;
25:16 what type of exercise;
25:17 what kind of stress is in her life,
25:19 and what has been in her life for the 50 years or so
25:22 before she goes through the menopause.
25:24 So in other words, looking at a natural state then would
25:27 cause them to actually look at all these things
25:29 throughout their life rather than -
25:30 Okay, we could do whatever we want until we get to
25:33 that state... Is that what you're saying?
25:34 Absolutely... I think that what we find is that in
25:38 Western society, in the United States in particular,
25:41 we find that we live almost unnaturally, I would say.
25:47 We eat foods that stimulate.
25:50 We keep hours that stimulate.
25:53 We have lifestyles that stimulate.
25:56 We have a lack of exercise.
25:58 And all these things create tremendous stress on the body
26:02 that when a woman then goes through the menopause,
26:05 she starts feeling things being out of balance,
26:10 and all of a sudden, it starts clicking for her.
26:13 There is something not right here.
26:15 There is something out of balance,
26:16 and so she comes to me to say - Help me get back into balance.
26:20 And what she's really looking for is a pill.
26:23 And so it's very easy to give her estrogen, for example,
26:26 because what we've thought is that she's estrogen-deficient
26:29 So it makes some sense to give her estrogen,
26:33 but MAYBE that's not why she's out of balance.
26:36 Maybe she's out of balance because of her diet.
26:38 Maybe she's out of balance because
26:40 there is stress in her life...
26:41 And, I think we need to look at those underlying causes
26:45 that are impacting her at the menopause.
26:48 As a Christian physician, all of these stages of transition...
26:52 Do you find that at these times,
26:54 people are very open spiritually?
26:56 Do you have these kind of conversations ever with them,
26:58 or do you see that as an opportunity for us to
27:01 maybe reevaluate our lives in that way?
27:04 Absolutely - Anytime we have big changes,
27:07 we go into transition, we're open to other changes
27:13 because we're searching.
27:14 I think health is related to spiritual things in that
27:22 to be healthy, we need the spiritual side of life.
27:26 I really think that that is important; I mean,
27:30 what a time of transition and
27:32 what an opportunity that you have.
27:33 We're glad that men like you are there to be able to
27:36 help us and help the ladies with these different problems.
27:40 You've been looking at "Health for a Lifetime"
27:42 and we hope that you have enjoyed this program.
27:44 We hope that it will help you in the different
27:46 transitions in your life.
27:48 We hope that, as a result, you'll have
27:50 Health that Lasts for a Lifetime!


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Revised 2014-12-17