Health for a Lifetime

The Wonderful Mind

Three Angels Broadcasting Network

Program transcript

Participants: Don Mackintosh, Neil Nedley

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Series Code: HFAL

Program Code: HFAL000062


00:45 Hello and welcome to "Health for a Lifetime"
00:47 I'm your host Don Mackintosh
00:48 and today we're just delighted that
00:50 Dr. Nedley back with us.
00:51 Welcome Dr. Nedley!
00:52 Thank you, Don. Very good to be here.
00:54 Today we're going to be talking about something that's
00:58 very vital... It's very important.
00:59 It's the BRAIN! Yes
01:01 And, you know, details concerning the brain.
01:07 I understand that recently you've been working on a
01:09 book that's going to be released,
01:11 or maybe will be released by the time people see this...
01:14 about the brain, but more specifically about
01:17 depression and the brain. Yes
01:19 And so, in this segment, we want to talk a little bit about
01:23 the brain, and what about the brain?
01:26 What makes it so special?
01:27 Well the brain is actually the most complex structure
01:32 known to human beings at this time,
01:35 and when you consider the space shuttle,
01:38 when you consider all of the structures that are known to man
01:42 this 3-1/2 pound structure is actually more complex
01:47 than ANY other structure known at this point in time.
01:52 It has 100 billion neurons.
01:55 A 100 billion neurons; I don't know how you would
01:58 picture 100 billion of something.
02:00 The neurons are actually the brain cells that do
02:02 the communication... do the thinking.
02:04 There's 100 billion of them, and there's even MORE
02:07 supporting cells in the brain.
02:10 And, it's just phenomenal when you consider
02:14 that that's all just encased in 3.5 pounds.
02:17 So the DNA that's been kind of decoded and whatnot
02:24 it just pales in comparison to all the different things
02:28 that need to be decoded to understand the brain.
02:30 Yes, it really does.
02:32 Now the DNA is there in each one of the neurons,
02:35 but the amazing thing is most organs in the body
02:39 have around 10 different types of cells.
02:42 The brain has thousands of different types of cells.
02:47 So your heart would have like 5-10 different types of cells,
02:53 but the brain has THOUSANDS!
02:56 Thousands, and each one of them is different as far as their
03:00 connections are concerned, and each one of them
03:04 has an important function to play.
03:07 So, these thousand different types,
03:09 how do they communicate with each other,
03:10 and how do they get along? How does it work?
03:13 Well the average neuron in the body actually has 1,000
03:17 different connections with other neurons.
03:20 Some neurons called "Purkinje cells"
03:23 connections...
03:26 Just 1 neuron, 200,000 connections with other neurons.
03:31 So that's like going into your house and having
03:33 200,000 outlets but it's all in the size of one cell.
03:36 All in the size of one cell. Wow!
03:41 It is an incredible structure...
03:44 And then the communication actually occurs
03:47 where those synapses are...
03:49 What we call the synapse; that's where one neuron
03:52 is actually touching, as it were, another.
03:56 It actually doesn't touch, it comes very close,
03:58 and it communicates through chemistry
04:00 from one neuron to another.
04:03 Is there any electricity in the brain?
04:04 Oh yes! In fact, that's how this communication takes place,
04:09 is through electric current.
04:11 One neuron will fire electricity and at the end of that electric
04:17 current, a chemical is released to then make the other
04:21 neuron know that it has communicated with it.
04:23 So the electricity just then triggers a certain type
04:26 of chemical, it could be different in one case or another
04:29 There are different types of chemicals?
04:31 There are different types of chemicals.
04:32 There are well over a thousand different types of chemicals
04:36 actually made in the human brain that are going through
04:42 this communication process.
04:43 Amazing! We're sitting her in a studio that probably,
04:45 I don't know, it may have maybe 1,000, or 2,000,
04:49 maybe 3,000 connections... I don't know.
04:52 We have all these lights around and different things...
04:54 haven't counted them up, but that's just one cell,
04:56 and then that's amplified by...
04:59 what did you say... 100 billion! That's right.
05:04 Well, what about those different chemicals...
05:09 Can you tell us a little bit more about those.
05:10 So I understand, probably a nerve impulse comes down
05:13 sort of like a domino chain down one of those...
05:18 Explain what happens...
05:19 Well, it actually goes down the axon.
05:23 The axon is the long portion of the nerve
05:26 where the electric current is transmitted.
05:29 And then that axon then branches out sometimes 100,
05:33 sometimes 1,000, sometimes more...
05:36 into the receptacles of the other neurons.
05:40 And in that synapse area, there are a number of
05:43 chemicals that can be released.
05:45 One of the most common is glutamate.
05:47 Glutamate is a stimulating chemical...
05:51 And then there are inhibitory chemicals,
05:53 and then there are modulating chemicals...
05:56 that are very important in that synapse area,
06:00 or where one neuron is communicating with another.
06:03 So glutamate then stimulates...
06:05 Is that like, would you call it an excitotoxin?
06:10 Or maybe not a toxin, but, you know,
06:13 they have those things that they say...
06:14 If you eat them, they're going to
06:15 excite your brain or different things.
06:17 Yes, this will excite... It actually, since it's
06:20 stimulating, it's called an excitatory neurotransmitter.
06:26 But it's not a toxin. It's not a toxin.
06:28 Now, of course, in excess, it could be a toxin.
06:32 And it can actually stimulate the nerve cells so much
06:35 that it destroys the nerve cell.
06:37 But we're talking about something that is
06:40 not a healthy portion.
06:42 So when you think or you are excited,
06:45 your brain then releases a glutamate-type substance
06:48 or is it the other way around?
06:50 Well actually, the glutamate would produce the excitement.
06:55 And how that all works, we probably don't
06:57 understand yet, do we?
06:58 There's much about the brain we don't understand.
07:01 We're actually piece-by-piece unfolding
07:04 more mysteries as the weeks go by.
07:06 So what would dopamine be?
07:08 Dopamine is actually a modulating chemical.
07:12 It doesn't stimulate, and it doesn't inhibit.
07:14 It actually modulates, and to illustrate this
07:18 glutamate would be playing the flute, providing the air
07:24 to produce the sound...
07:27 And the dopamine would be playing the keys
07:30 in order to make the melody of that sound.
07:32 It would be the placement of those.
07:34 So dopamine, that's something we normally hear about
07:37 and, you know, we normally hear that it kind of
07:40 soothes us, and all those different kinds of things,
07:43 and is that correct?
07:45 Well, dopamine has a modulating effect.
07:48 It can have a soothing effect in certain instances,
07:50 but it can also be very important in regards to motion.
07:54 Those that don't have enough dopamine
07:56 end up with Parkinson disease,
07:58 and that causes a stiff walking gait,
08:01 a stooped over gait, and actually, a decreased ability
08:05 for the entire brain to function very well.
08:08 So, we have some public officials in government now
08:15 that have Parkinson disease;
08:16 we hear about that from time to time.
08:18 The fluidity of movement and the tremors and whatnot
08:22 that's all related to that,
08:23 but can they still think things through well?
08:26 They can think things through
08:28 pretty well up to a certain point...
08:30 And then in the later stages of Parkinson disease,
08:33 it actually causes dementia which means an inability
08:37 to be able to think things through clearly.
08:40 So the dopamine then probably is just a
08:43 pretty big part of the brain...
08:44 How much of the brain then has that capacity?
08:48 You would think it would be a very important aspect of
08:51 just about every neuron...
08:52 Gotta have the "dope.. amine"
08:53 I mean, the dopamine, right?
08:55 Actually, only 200,000 neurons produce dopamine.
09:00 200,000? You said there was over a billion, that's not very many.
09:03 Yeah, 100 billion, so 200,000 to 100 billion
09:07 is a VERY small amount of neurons producing dopamine.
09:10 But when you consider that each one of the neurons has about
09:15 a thousand ways in which it can have that
09:18 dopamine communicate with another nerve cell,
09:21 and then those nerve cells have a thousand ways
09:24 of communicating with other nerve cells,
09:28 if you have the dopamine content lowered in those
09:30 200,000 cells, it can have almost an entire brain effect
09:35 as far as its impact.
09:38 So even though there's a small amount of cells that
09:41 produce dopamine, if they don't they're so well-connected
09:44 that everything comes to a
09:46 grinding halt, so-to-speak. Correct
09:48 Wow, that's sort of like, you know, we study in the Bible
09:52 and we see the remnant, and we see how important
09:55 the remnant were throughout the Scriptures.
09:57 The dopamine would probably be sort of like the remnant.
10:00 That would be a good illustration...
10:02 A very small portion, but having
10:05 a profound effect upon the entire brain.
10:08 So, are there treatments when we have Parkinson disease,
10:12 and those different kinds of things that they're developing
10:14 Well there are treatments, yes...
10:15 we try to provide more dopamine.
10:17 And, of course, we can do that through chemistry
10:20 of providing more dopamine intake,
10:24 and then part of that dopamine goes to the brain,
10:27 and then that dopamine can then be used
10:29 to communicate with one nerve cell.
10:31 However, that's not all that great a mechanism.
10:35 It does work... we have ways of trying to get more
10:38 dopamine in, and even what we call "dopamine agonist"
10:41 which ACT like dopamine in the nerve cell.
10:44 But we're just providing it in the neuronal junction
10:47 without the nerve cell itself producing it,
10:50 and releasing it...
10:52 And so, that gets into some side effects, and that's why
10:56 all Parkinson's medications can have side-effects.
11:00 If we could get the nerve cell itself to produce it and
11:03 release it when it's supposed to, we could have a treatment
11:06 that would have no side-effects.
11:08 Yeah, in taking care of some Parkinson's patients,
11:12 I've noticed that they will be on a certain medication
11:15 for a certain amount of time, like Sinemet, or whatever,
11:18 they use nowadays, I'm not sure...
11:20 and then they have to go off.
11:21 they still have to go off of that for a while
11:23 because they have those reactions.
11:26 Well, so we have the stimulating;
11:28 we have the modulating, and then we had the inhibitory.
11:31 What would be a common inhibitory thing that maybe
11:33 we've heard of before that you could explain to us?
11:36 Well, there's a relative of glutamate...
11:39 It's probably not well-known that it
11:41 actually is an inhibitory chemical.
11:43 There's actually more inhibitory chemicals,
11:45 than there are excitatory chemicals in the brain.
11:48 The brain is also meant to have an important function
11:53 that being a BREAK on behavior,
11:55 and a BREAK on overstimulation...
11:58 And so there are several inhibitory chemicals
12:01 to try to prevent glutamate from getting out of control.
12:04 So it is a balance of powers.
12:05 It's just like, sort of, the government over the system...
12:08 The brain kind of helps us... It's our legislative branches,
12:12 so-to-speak!
12:14 Yes, it's very important for there to be
12:17 a balance in the brain.
12:18 And a balance in many forms.
12:21 You know, there are just 3 balances in our government
12:25 here in the United States;
12:26 there's a lot more balance taking place in the human brain.
12:29 So we've talked about how complex the brain is...
12:33 We've talked about the different over 100 billion
12:36 different types of neurons with over 1,000 connections;
12:42 some have 2,000 connections each.
12:44 We've talked about the different chemicals that are released.
12:47 Some with 200,000 connections actually.
12:50 We're going to take a break here in just a minute,
12:53 but let's introduce something that we want to talk about
12:55 This is amazing... the Bible says we're
12:57 fearfully and wonderfully made...
12:59 And certainly with a brain, that is true,
13:02 but is there any flexibility?
13:05 Does it HAVE to work this way or that way?
13:10 Is the brain pretty much, you know, you take your computer
13:12 and you get... here is some rapid access memory,
13:15 here's some RAM memory.
13:16 We're just going to put that in,
13:18 and that's the way it's gotta work,
13:19 and if it's not there, it's not going to work.
13:20 Does the brain have any flexibility?
13:22 Yes, it has a lot of flexibility,
13:24 and that's really what makes it different from these
13:26 simple computers that are being used today.
13:29 I say "simple" because we look at the new computers,
13:32 and say, "Wow, how much better
13:33 and how much more complex they are. "
13:35 But, in relationship to the human brain,
13:38 they are very, very simple structures.
13:42 We've been talking with Dr. Neil Nedley,
13:44 and we've been talking about the AMAZING brain.
13:47 We've talked about how complex it is.
13:48 We've talked about... well, lots of different things
13:52 about it, but the most interesting thing
13:54 we've just been mentioning is that there is some
13:55 flexibility in the brain, and it can do different things...
13:59 And when we come back, we're going to find out more
14:00 about those different things, so we hope you join us!
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15:06 Welcome back, we've been talking with Dr. Neil Nedley,
15:09 and we're talking about the brain.
15:12 You had mentioned something that was fascinating before we left;
15:15 that the brain really has some flexibility,
15:17 and that gives us hope!
15:20 We don't have to just be...
15:21 It's an organic organism; it can reposition as to what we need.
15:26 Yes, actually just a thought process itself can actually
15:31 weaken some associations with other neurons, and strengthen
15:36 other associations with other neurons.
15:39 And, a memory, a thought to produce some memory
15:42 can actually disconnect a neuron from some other neurons,
15:47 and then actually have that neuron be associated with others
15:51 And so we have the ability, so-to-speak, of having this
15:56 brain be VERY flexible.
15:58 It's not like a computer where its circuits are there,
16:03 and the only way you're going to change it is to go in
16:05 and do surgery on the computer which would be having your
16:08 hardware person come in and do things.
16:10 You can actually have the thoughts themselves
16:14 change the makeup of the brain!
16:16 So that's what unplugs and plugs things back in,
16:19 and so our thoughts, and what we focus on,
16:22 and what we think about is very important!
16:23 Very important... particularly when those
16:26 thoughts become habitual.
16:28 Habitual thoughts, there are very...
16:31 we could call them expressways, or interstate highways
16:36 which are well-traveled, and once we get into a habit,
16:40 we have interstate highways in our brain that are NOT
16:44 easily destroyed unless we go a different route
16:48 and don't travel that highway for a very long time.
16:51 So how can we be delivered about that as, you know,
16:54 we hear a lot about the different right brain/left brain
16:56 and all this kind of different kind of things...
16:58 How can we be delivered about having a healthy brain?
17:02 I'd like to say there's been an over-emphasis, really
17:05 on this left brain/right brain things.
17:08 I hear some individuals, and even some scientists
17:12 talk about this, and there is some truth...
17:15 the left brain tends to be more objective;
17:17 the right brain tends to be more creative.
17:19 But that is an over-simplification
17:22 of the process.
17:23 The frontal lobe is to be the control center
17:26 of the entire brain, whether it's the left or the right brain
17:30 And the left side of the frontal lobe,
17:32 and the right side of the frontal lobe have some
17:33 very similar functions, and try to simplify
17:39 the brain by breaking it up into these 2 sides,
17:42 is really doing a disservice to it.
17:45 Doesn't understand the complexity of all
17:47 those different connections that we talked about. Exactly
17:50 Okay, I imagine then, do we need to talk anything more
17:56 about the different lobes of the brain and what they do
17:58 in talking about complexity of the brain?
18:01 Well, there are specialized areas of the brain...
18:04 The occipital lobe, for instance the back portion of the
18:07 human brain, is actually where your vision is centered...
18:11 But it's much more than just a visual area.
18:15 It actually takes a look at where things are in space,
18:18 the color that they are, the hue that is coming in,
18:22 and also it's very important in regards to geometric skills,
18:28 and even spatial engineering-type skills
18:30 involve the occipital lobe.
18:32 So anything to do with spatial orientation, colors,
18:37 and those type of things would involve the occipital lobe...
18:40 so geometry, all those different kind of things...
18:42 Do you develop... is balance back there too?
18:44 Balance is even further back and it's a little lower.
18:48 It's in what we call the "cerebellum. "
18:50 And, this is a very important area, particularly for certain
18:54 creatures such as monkeys that are very athletic,
19:00 and very smooth in their going upside-down,
19:03 swinging by their tail, etcetera.
19:05 And our athletes of today have to have well-developed
19:08 cerebellums in order to be good in their athletic sport.
19:11 With all this complexity, I'm sure there could be problems.
19:14 Oh yes, problems develop.
19:18 In fact, problems more commonly than you might
19:20 imagine, Don.
19:22 Only 22% of individuals, from the time they were born,
19:26 will have a mental illness at some time during their lifetime.
19:31 So 22 out of 100 people are going to have,
19:32 what we would call, a mental illness.
19:34 What do you mean by a mental illness?
19:36 A mental illness is beyond just feeling blue,
19:39 or just having a personality problem.
19:43 All of us, I would say, and probably 100% of us
19:46 are going to end up in some problem with our brain itself...
19:50 But that doesn't mean that we're going to have
19:51 a mental illness, per se...
19:54 That just means that we got off the right track,
19:58 and we had problems, as far as the brain development,
20:01 and making appropriate decisions, etcetera.
20:04 But a mental illness goes beyond that.
20:06 A mental illness would involve, for instance, major depression..
20:10 where instead of just feeling sad or empty, we also
20:13 have a constellation of symptoms that bring about this
20:17 major depression.
20:18 We also have schizophrenia, bipolar disorder,
20:22 affective disorders such as anxiety disorders,
20:26 which can produce what we call obsessive compulsive disorders,
20:31 phobias, or even chronic anxiety in and of itself.
20:37 These are disease processes of
20:41 the brain that need special attention.
20:43 The good news about these diseases though, Don,
20:46 is that about 90% of them are actually reversible
20:51 through finding the cause, and getting on the
20:54 appropriate treatment.
20:56 Okay, so you gave us a lot to think about there...
20:59 22 out of every 100 people are going to have this
21:02 at some time in their lives;
21:03 some major depression...
21:06 Well let's talk about that... What about major depression?
21:08 How many of that 22% are going to have the major depression?
21:11 10% of individuals will develop major depression.
21:15 So that's a BIGGIE! That's a biggie.
21:17 And I know that you're actually writing a new book on that
21:22 because you see so much of that, and we want to talk
21:23 a little bit more about that.
21:27 And then, how does it breakdown after that?
21:29 Well actually, the most common
21:32 mental illness is chronic anxiety.
21:34 We'll deal with that as well in our book...
21:38 and it does have a tie-in with depression.
21:40 About half of patients with
21:42 chronic anxiety will end up with depression.
21:45 And then other common disorders are
21:46 obsessive compulsive disorder...
21:48 Meaning just a certain routine you can't get away from,
21:52 or you have to do it this way or else
21:54 you have a lot of anxiety as a result. That's right, exactly.
21:56 And then there are simple phobias...
22:00 You know, fear of being in enclosed spaces, for instance.
22:04 What about fear of snakes?
22:05 No, fear of snakes is not classified as a mental illness.
22:10 It's very good to be afraid of snakes.
22:13 Well, I know that some people watching today will be
22:15 very happy that that's not.
22:17 What would be a bad phobia?
22:21 Like you said, fear of people?
22:22 Would that be considered a mental illness?
22:25 Yes, fear of people is actually a classified mental illness
22:29 where you have fear of actually getting in a group of people,
22:33 or a fear of even going to a social encounter
22:36 because of that phobia, unnatural.
22:40 So you said something very encouraging though
22:42 that 90% of these can be reversed.
22:44 Let's talk about the discouraging first part of
22:47 that statement, and let's talk about the encouraging next.
22:49 The discouraging part is that 10% that can't be.
22:52 What's that 10% that really can't be addressed?
22:55 Well actually 10% in regards
22:57 to standard ways of looking at this.
23:00 I actually am more optimistic.
23:02 I think there's probably, a far greater than a 90% chance...
23:07 if we really take a look at the root cause,
23:09 and try to find the cause of these diseases,
23:11 I think we'll do a lot better than even 90%.
23:14 But out of those that 10% or less,
23:17 a lot of it has to do with how their brain was formed
23:21 during the time when it was in the mother's womb.
23:25 So some genetic things, some things that come as
23:28 result of drug abuse by the parents, those kinds of things
23:31 where the wiring... the 1,000 circuits per cell
23:35 are just not there... that kind of thing. Right
23:38 And that's what accounts for that 10% that
23:40 it's a little bit more problematic in reversing it
23:44 without divine intervention which, of course,
23:47 God can do ANYTHING! Exactly
23:50 And, the other thing I would like to bring out is
23:53 even though you have the genetic basis for mental illness
23:56 does not mean you're in that 10%.
23:59 If your mother and father were both depressed,
24:01 or even if they both committed suicide,
24:03 that does not mean that you are resigned to get
24:06 major depression, no matter what you do in your lifetime.
24:08 And you hear that a lot...
24:10 A lot of people say, "Well they committed suicide so
24:12 you must be headed that way. "
24:15 But, for the person that's listening today,
24:17 that's just not true. No, it's not true!
24:19 It does make them have a greater tendency,
24:22 BUT if they actually get on the proper program,
24:26 lifestyle-wise, and thought process-wise,
24:28 they can completely avoid the major depression
24:31 that their parents had.
24:32 Does this mean medication...
24:34 when you say reversing it, does that mean medication
24:37 in that 90% of the cases that are going to be reversed?
24:40 It could mean medication for the short-term.
24:43 In some cases, it might mean medication for the long-term.
24:47 But, in dealing with major depression, for instance,
24:50 we're able to get major depressed patients
24:53 OFF of their medication in about 90% of cases,
24:56 and NOT have a relapse into their depression...
24:59 if we get to the cause, and put them on the right
25:02 lifestyle and nutrition treatment program.
25:06 Dr. Nedley, you're a Christian physician.
25:07 I mean, that's one of the great benefits,
25:10 and I understand that in medical schools across the country,
25:12 they now even have all these seminars on spirituality,
25:17 they're bringing all of this in, and I think that they
25:20 don't pick and choose between religions and different things,
25:23 but as a CHRISTIAN physician,
25:26 what have you seen in the research and whatnot
25:29 that kind of ties this all together
25:32 in terms of addressing it?
25:33 What brings this all together, Don, is where scientists
25:38 are converging on the area of the brain that tends to
25:42 bring out all of these mental disorders...
25:44 and that is the frontal lobe of the brain.
25:47 The frontal lobe of the brain is now the
25:50 CENTER of where depression originates from.
25:53 Before, we used to think it was the emotional area
25:56 of the brain because depression has so much to do with emotions.
25:59 But actually, it's due to the control center of the brain...
26:03 having a decrease in circulation and a decrease in activity
26:07 that brings about depression.
26:08 I happened to listen to the top bipolar researcher
26:13 in the United States just a few weeks ago,
26:16 and he says that bipolar disorder, we are now finding out
26:20 is originating in the frontal lobe of the brain.
26:22 Schizophrenia has to do with the frontal lobe of the brain.
26:25 And just about every one of these mental illnesses
26:28 converge on the frontal lobe of the brain
26:31 a problem with the control center that then brought about
26:34 the mental illness.
26:36 And, as a Christian physician, what is meaningful to me
26:39 here is the frontal lobe is the CENTER of morality,
26:43 spirituality and the will.
26:45 Without the frontal lobe, there is no spiritual person,
26:48 there is no will.
26:49 And so, this is vitally important to understanding
26:56 these mental illnesses and treating them.
26:58 So and in treating this, the 22% of Americans
27:01 that have mental illness, and you have given us
27:04 OPTIMISTIC words that 90 and even more than that
27:08 90% or more of them can REVERSE this...
27:13 What should they do to build their frontal lobe
27:16 to either prevent or perhaps REVERSE these mental illnesses?
27:22 Well in a statement, it would eating appropriately,
27:26 drinking appropriately, being on the appropriate lifestyle,
27:30 and thinking appropriately.
27:33 That sounds like a Bible text!
27:35 Whatsoever you do... whatever you eat, whatever you drink,
27:40 whatever you do, do all to the the glory of God. Wonderful!
27:45 Thank you so much for joining us, Dr. Nedley.
27:47 And thank YOU for joining us.
27:49 We hope that what you've learned has been a help to you.
27:51 If you want more information about Dr. Nedley's book,
27:54 call 3ABN, and we hope you join us next time!


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Revised 2014-12-17