Made for Health

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Series Code: MH

Program Code: MH240007S


00:01 Jumping rope takes rhythm, you may think some got it
00:03 and some don't but that's not entirely true.
00:06 I've got rhythm and you do too, it's what we were made for.
00:33 You've got rhythm, we're talking about physiological rhythm
00:38 the beating of the heart, the cadence of your breath,
00:41 rhythm of walking and running, day and night, women having
00:45 monthly cycles, digestion is even rhythmic,
00:48 yeah, you've got rhythm.
00:50 We're not necessarily referring how you move to music
00:53 or the beat of two jump ropes going on at the same time,
00:56 or if you play an instrument even though that's great to have
00:59 But our body has clocks that keep time, Cellular rhythm,
01:04 and it's how they conduct their functions instinct with
01:07 one another, that's what's is important.
01:09 The problem is we can get out of sync with nature
01:12 with each other, and with the organization's that we work for
01:16 but what is even more dangerous is when we get out of rhythm
01:19 with ourselves, this is our topic for today.
01:23 It has multiple elements of rhythm, it's all about rhythm.
01:28 Our body has a central body clock which is in our brain
01:32 in our hypothalamus and it has also peripheral body clocks
01:38 in each cell of our body.
01:40 So, our system is based on clocks.
01:43 Well, it's really interesting because our bodies actually have
01:47 a circadian rhythm and so what that means is that
01:51 our bodies do best when we have regular structure
01:56 and it knows what to expect.
01:58 And that circadian rhythm gets set by the body's master
02:06 clock which is in the hypothalamus and it's largely
02:10 responsive and the reason that that takes place
02:13 is in response to light.
02:15 Now the central clock in the brain is entrained by the light
02:20 and darkness cycle, day and night, when do you turn off
02:27 your lights, when do you wake up? When are you exposed to
02:31 sunshine? Those are the most important factors in training
02:35 your central clock.
02:37 When the retina in our cells or in our eyes gets
02:44 stimulated by light,
02:46 there are cells in the retina that are specifically
02:51 sensitive to that Blue Light and that in turn then will
02:56 send a signal to a part of the brain, called the hypothalamus
03:00 and that sets what we call the circadian rhythm or the body's
03:05 clock for the day.
03:06 So we have a master clock in our brain that is set by light
03:10 got it, our cells below our neck also have clocks and they are
03:15 set differently as we are going to see.
03:16 Some of our doctors refer to them as central and
03:20 peripheral clocks and these clocks are what make up our
03:23 circadian rhythm. The master central clock gets wound up by
03:28 and gets set with light and dark cycles.
03:31 It makes me realize that we were designed with this connect
03:35 with nature, specifically the sun that it is ninety three
03:39 millionish miles away.
03:41 We kind of think of ourselves as autonomous from nature
03:44 but in actuality, nature influences us physiologically
03:48 and mentally.
03:50 If we try to live autonomously, it obviously doesn't work
03:55 so well and even when we kind of our own circadian rhythm
03:58 by being up all night...Like maybe we're a shift worker
04:03 or we have to be up all night and we're using artificial
04:08 light and then we go and we try to use blackout curtains
04:11 to sleep during the day. We're fighting our natural
04:14 tendencies and even there studies have shown that
04:17 it really does stress people significantly and their
04:20 mental health issues go up even if they're trying to
04:24 live as best they can to counteract that.
04:28 The best way to reduce chronic inflammation is to have
04:33 a regular cycle.
04:35 There is something to be said about the regularity of this
04:37 sleep pattern as well so are they staying up until two
04:40 in the morning one night and then they are trying to go
04:41 to bed at nine the next night you know just the irregularity
04:44 the body likes to work on rhythms and our hormones
04:47 and all of those things are set up in rhythms and so
04:50 if we aren't regular with our rhythms and with our sleep
04:53 as one of the big rhythms, then it just becomes more
04:55 complicated as well. Hormones are definitely
04:58 circadian, you know we talked about Testosterone a little bit
05:02 earlier. Testosterone is very circadian in men for example
05:08 the testosterone level is higher in the morning
05:10 and it wanes as we go throughout the day and it's at its lowest
05:14 by mid-afternoon.
05:15 And when we are not in a routine, the hormone levels
05:23 can get all out of whack.
05:24 Based on what it gets used to it will actually start secreting
05:28 different hormones for example like cortisol and when
05:32 the cortisol starts peaking in the morning,
05:34 then that tells your body, hey, you know it's time
05:38 to be alert and awake and to get going for the day.
05:41 And that's actually a good thing, now, on the other hand
05:44 the body also starts knowing like based on when it gets
05:48 dark and just the regularity if you schedule like okay,
05:52 it's time to start secreting more melatonin which
05:53 will prepare you to fall asleep and get a good night's rest.
05:57 And then there's so... I mean those are just two
05:59 simple examples, there are so many different hormones
06:02 that the body needs to know what time do I secrete
06:06 that so that my body can function properly and if you
06:10 do that regularly, then your body can be running like
06:13 a well-oiled machine.
06:15 I told you, you got rhythm, even down to the hormonal level.
06:19 How important is it to live in harmony with this rhythm?
06:23 Well, it's actually very important, one simple
06:26 example is a study they did at Harvard where they took
06:30 ten people and they started shifting and messing with their
06:33 circadian rhythm and what they found was that those people
06:38 actually lost the ability to regulate their blood sugar
06:42 properly and entered into a pre-diabetic state.
06:45 And it also really messed up their levels of leptin which
06:50 is actually a hormone that secreted and tells your body
06:54 okay, you're full you don't need to eat more and so they
06:57 lost that ability to regulate their appetite properly.
07:01 So, the central and the peripheral clocks need to be
07:06 synchronized. Now what happens? why do we even care?
07:11 Why do they need to be synchronized?
07:14 A good example is in shift workers, where both of these
07:19 clocks are just uncoupled and they have a high risk
07:24 of developing cardiovascular disease, they have a higher
07:28 risk of developing obesity and also type II Diabetes.
07:32 In a home that I grew up in, there was a clock that sat on
07:36 the mantel above the fireplace. I remember my dad taking
07:39 a special key and winding it up periodically so it would keep
07:43 accurate time. The special key that keeps the master clock
07:46 in our brain wound up his day and night like you.
07:49 But the body clocks below the neck are peripheral clocks
07:54 are set by when we eat.
07:56 When we east we set trillions of cellular circadian clocks
08:00 in the body, when we eat and sleep irregularly, we get
08:05 totally out of rhythm.
08:07 Sleep the same time, wake up the same time.
08:09 The cycle is important as how we eat because
08:13 the way we eat and the times we eat actually matter
08:16 in regards to the pattern.
08:18 Research has shown that being consistent with the times
08:22 when we eat the meals is really important.
08:25 There's quite a few perspective studies looking at eating
08:30 our meals regularly verses irregularly.
08:33 And those people who don't have and consistent times for
08:37 their meals and just eat at erratic times,
08:41 they have about a 50% bigger chance of developing obesity
08:48 and metabolic syndrome type II Diabetes compared with those
08:51 who eat their meals at regular times. When we say regular
08:56 we mean consistent times, that means you eat for example
09:00 breakfast around 7:30, but if it's 7:25 or 7:40 that's still
09:07 fine, that's still one consistent time.
09:10 We don't mean having meals every two or three hours
09:16 or something. We mean having consistent times for your meals.
09:20 Well, ideally if you can have a regular time for breakfast,
09:25 lunch, and then if you are going to eat a third meal,
09:27 dinner, within an hour or so, that's the idea that if you're
09:33 eating at regular times, sleeping at regular times,
09:35 and your body gets all out of whack and it gets actually
09:39 overly stressed and it can't function properly.
09:42 It's not just what we eat but when we eat.
09:45 What if we ate food more on the time than on the urge
09:49 because it is available or being offered to me,
09:52 or I just happen to be driving by?
09:54 It would probably radically change our health
09:56 our weight and our relationship with food.
09:59 Even our GI system, even though it's not the master clock
10:04 it actually even has its own circadian rhythm,
10:06 every one of our organs actually has its own circadian rhythm
10:11 and so that's why it's so important when we think about
10:13 meal times. Our bodies are expecting certain things
10:17 at certain times and when we cooperate with that and
10:20 we actually train it the right way, then we're going to have
10:23 the most efficient ability to digest things properly
10:27 and to function well overall.
10:30 One of the earliest studies in Chrono nutrition
10:33 around 15 years ago, found that mice fed a high-fat diet
10:38 during the day when they would normally sleep gained
10:41 significantly more weight than mice fed the same high-fat diet
10:46 during the night when they would normally be awake.
10:48 This has been found true in humans as well.
10:52 A recent small study took 16 participants who were in the
10:56 overweight or obese range, they found that eating four hours
11:01 later for all the meals had profound effects on hunger,
11:05 and on the appetite-regulating hormones Leptin and Ghrelin
11:09 Which influences our drive to eat. Leptin signals I'm full,
11:14 not interested, don't want anymore.
11:16 Leptin was the one that decreased about 24 hours
11:20 when they were late eating compared to early eating.
11:23 In other words, eating late made the participants
11:27 more hungry and less likely to feel full for 24 hours.
11:32 They also found that when participants ate later
11:36 they burned fewer calories, saw biological changes that promote
11:40 fat growth not fat loss. And like Dr. Callovian shared
11:44 earlier, studies show that eating during the nighttime
11:48 like many shift workers do, can increase blood glucose
11:52 levels. Next, Dr. Callovian applies the concept of
11:57 Chrono nutrition to helping with jet-lag.
12:00 Chrono nutrition is an emerging area of research
12:05 trying to help us synchronize the body clocks, the central
12:09 and the peripheral body clocks and what goes into it.
12:13 Intermittent fasting, the right timing of the meals,
12:17 and the right frequency, no snacking, and eating only
12:22 two to three meals a day is a big part of it.
12:26 So, what can you do to synchronize the body clock?
12:29 One of the most important ways is intermittent fasting
12:34 and the right timing of your foods.
12:38 So, a simple example would be when you're for example traveling
12:42 and you're changing time zones, can you do something to make it
12:46 easier on your body? Absolutely, for example,
12:50 you take a flight to Europe and Europe is six hours ahead
12:56 and you are leaving in the evening.
13:00 The most important thing is to realize what the time
13:05 in Europe is when you are leaving and you know
13:08 that when you are leaving in the evening it's already
13:12 early in the morning when you are supposed to be sleeping
13:16 so you shouldn't eat anything when you are leaving
13:21 no matter what they are serving on the airplane.
13:23 You shouldn't be eating anything to make it easier
13:26 on your body and when you arrive in Europe, which will be
13:29 probably in the morning or just before noon,
13:34 you should really eating a lot on the good stuff
13:40 to tell your body good morning, it's time to start working
13:45 and then stop eating in the early afternoon again.
13:50 And that way your body will adjust quicker,
13:53 and that's just example when you're traveling.
13:57 But this is important on a daily basis for all of us.
14:00 How do we synchronize the clocks on a daily basis?
14:04 Breakfast is the most important meal of the day because that's
14:10 the jump start of your metabolism, it tells your body
14:13 it's day, it's time to start working...
14:16 Research shows that when people eat breakfast,
14:21 they burn more calories during their physical activity.
14:25 So, it really changes your metabolism for the whole day
14:31 so breakfast is the most important meal of the day.
14:34 And on the other hand, dinner should be the lightest meal
14:39 of the day and if you can skip dinner, you get extra points.
14:43 Because our ancestors got it right, eat breakfast like a king
14:48 lunch like a prince, and dinner like a pauper
14:51 because dinner tends to disrupt the body clock.
14:55 It tends to override all of the metabolic effects,
15:00 it tends to contribute to depositing more fat.
15:04 It's been shown that if you eat the same amount of energy
15:08 as breakfast, lunch, and dinner, you will deposit
15:12 most fat after dinner.
15:14 After the same energy you consumed, so the timing of the
15:19 meals is really really important.
15:21 When we look at the length of night-fast in the
15:27 Adventist Health Study too, we found out that having at
15:31 least 18 hours of night-fast was most beneficial
15:35 which gives us two meals apart eating two meal a day
15:41 about five to six hours apart.
15:44 So that sounds like the best plan.
15:49 It's really important that we do and intermittent fast for ideally
15:55 about five hours between meals and that gives the body a chance
16:01 to actually get into a detoxification mode.
16:07 If we are constantly eating snacks every two the three hours
16:11 the body's never able to properly detoxify.
16:13 So, basically having no calories between meals obviously
16:19 decreases your caloric intake right? that helps your body
16:23 get better at burning fat from you access fat tissue.
16:27 Okay, then you have at least 12 hours of no food
16:30 from the end of supper or the evening meal to the
16:33 beginning of breakfast and some people do better going longer
16:37 than that and occasionally doing an extended one-day
16:40 or two two-day water fast can be very beneficial.
16:44 But most patients prefer going to a breakfast/lunch
16:48 program so that they're not having any evening meals
16:51 so now they go to an 18-plus hour overnight fast
16:55 so that the body's burning fat on a daily basis at a heightened
17:00 level and that for many people gets them where they need to be.
17:04 And that's where two meals a day come into practice
17:08 the intermittent fasting on a daily basis. How you eat your
17:12 meals is also important.
17:13 Do you eat only a few times a day? Let's say two or three
17:19 times a day? Or do you snack? If you snack you disrupt your
17:25 body clock again. It's been shown that if you eat the same
17:30 meal in one sitting, and compare it to eating the same meal
17:34 in six small meals during the day, the thermic effect of food
17:39 the amount of energy that's released in the form of heat
17:42 after the meal will be bigger after the big meal.
17:46 So for your weight management it's really better to eat
17:50 fewer times a day and the research has shown that
17:54 two meals a day are actually even better than three.
17:58 I studied this subject at Loma Linda University analyzing
18:03 the data for more than 50,000 people from the study and
18:07 looking at how many times people we're eating and how they were
18:13 changing their body weight over the follow-up of more than
18:17 seven years. And what we found out was really fascinating.
18:21 We found a linear relationship between the number of meals
18:25 and how people were gaining weight.
18:27 So, when we put three meals a day as our reference group
18:32 snacking that means eating four, five, or six meals a day.
18:38 It was just like increasing their risk of gaining weight
18:41 over time. In contrast to eating two meals a day
18:46 where people who are eating two meals a day were better off
18:50 than people eating three meals a day.
18:52 This study was not the only one, there's also other studies
18:56 showing that two meals a day are actually better for
19:00 weight management and metabolism compared with three meals a day.
19:04 So if you can do it, by all means just skip dinner
19:07 and that's your intermittent fasting on a daily basis.
19:11 And also people who were eating breakfast were protected against
19:15 weight gain compared with people who were skipping
19:19 breakfast and people who ate breakfast as their largest meal
19:24 they were protected against weight gain even more than those
19:29 who ate their largest meal as lunch or dinner.
19:32 Now the peripheral clocks in each organ of our body
19:37 needs to be synchronized with the central clock and
19:41 that happens through nutrition clues.
19:45 That happens through cycles of eating and fasting
19:49 When do you eat? When do you start eating? when do you finish
19:54 eating during the day? And also through the composition
19:59 of the diet. What do you eat? High-fat diet for example
20:03 desynchronizes both of the clocks.
20:08 While a plant-based diet will help synchronize them.
20:12 But also, it comes down to the composition of the meals
20:18 high-fat meals tend to disrupt the body clock and delayed
20:24 the expression of clogged genes, there is clock genes in each
20:28 cell of our body and as the name of the gene suggests
20:34 these are important for the synchronization of the
20:37 peripheral clock and the central clock.
20:39 If we eat a high-fatty meal, the expression of the clogged
20:46 genes will be delayed and that also happens for example
20:50 if you wake up and don't eat your breakfast for a long time
20:54 until noon let's say. Some people do intermittent fasting
20:58 in this way, they don't eat breakfast, they eat lunch
21:01 and they eat dinner.
21:02 But guess what? That also delays the expression of the
21:07 clogged genes. So it's not ideal for the clogged gene
21:10 expression and the synchronization of the
21:13 body clock. More powerful is to start eating your
21:16 breakfast, eat only two or three meals a day and be done
21:21 in the early afternoon.
21:23 It matters as far as when we exercise, we know that if you
21:26 exercise in the morning your cortisol goes up
21:28 you also affect the metabolism, you affect mood,
21:31 you affect everything. Exercise is not just exercise,
21:33 it's the best mood-altering drug out there.
21:37 It's the best sleep-inducing. drug out there,
21:40 it's the best metabolic stimulant especially if its
21:45 done early. Your sleep patterns are programmed in you,
21:49 you can fight it but it's going to affect you long term.
21:51 You might not even feel tired because we have coffee,
21:54 you know we medicate ourselves and at night you knock yourself
21:58 out with alcohol which might knock you out but you're not
22:00 going to get into a deep sleep.
22:02 But your pattern is your pattern, your biology is your
22:05 biology, the parts that you don't need to fight,
22:08 so it's almost like that serenity prayer, you know.
22:11 God give me the wisdom so... where you can't change it, don't.
22:16 Where you can't defect it know it, live by it.
22:19 But where you can, then you alter it, fix it, change it.
22:23 And there a lot of things that you can't, you're circadian
22:26 clock is important, let's live by that.
22:30 You know, I hope after listening to today's episode, you're more
22:34 willing to take on the battle the battle against habits
22:38 We may have formed a practice for years, maybe it's lack of
22:42 structure, lack of rhythm to your day of night-time snacking.
22:46 I would encourage you to pick one thing, pick a time and
22:50 start working on this to get in sync with your inner rhythm
22:53 so you can live the masterpiece of your life.
22:56 But focusing on changing our behaviors to line with our
23:00 internal clocks, it is a challenge and it's a battle
23:03 that's worth tackling.
23:05 Make regular times for eating, regular times for sleeping,
23:09 and then we've talked recently here about the idea of
23:14 the weekly rest as well.
23:15 And so I think those factors. are huge and especially my
23:20 patients that have bipolar because bipolar is largely
23:23 related to a circadian rhythm disturbance, it's so important
23:28 but for all of us, it's important but especially I emphasize it
23:30 with bipolar patients.
23:32 Now let's talk about the other clock which is behavior
23:35 which is habit, we are creatures of habit, we've heard that
23:40 but we are understating that.
23:41 We're not just 20% habit, we're not just 40% habit,
23:45 we're mostly habit, even our political ideology after a while
23:50 becomes habit. It was a seed that was planted and then
23:53 then we just create thoughts around habits if somebody
23:55 throws something without even thinking we know what comes out
23:58 actually, we don't know what comes out, it comes out.
24:00 Habit and rhythm is every, it doesn't mean that we don't
24:06 like it, it doesn't mean that we fight it,
24:08 it means that we have to be aware of it so it doesn't
24:11 overtakes us in the wrong directions, it doesn't alter our
24:17 patterns of living in a complex world and we have some
24:21 measure of control over that rhythm.
24:23 Our habits are created by repeated behaviors that are
24:27 reinforced. Then after a certain pattern which is rhythmic
24:32 it becomes inculcated in your body because your dopamine
24:35 pathway, which is also rhythm. Your dopamine is not released
24:39 in one even...it's actually rhythmic release.
24:42 Then it becomes part of your very existence
24:45 So, were all about rhythm, we're all about pattern...
24:48 The circadian clock actually controls not just sleep,
24:54 indirectly it controls your food intake, and how it affects
25:00 the chemicals that make you full, satiety and hunger,
25:05 it affects mood with the cycles.
25:07 We see this in dementia where later in dementia where
25:10 people have this sun downing. Later in the daytime, they become
25:14 more confused, more agitated as not just because light is
25:19 going down, it's actually the clock, the cycle.
25:22 So, that cycle is critical for us to be aware of first
25:25 with sleep, sleep the same time wake up the same time.
25:28 The cycle is important as far as how we eat,
25:32 because the way we eat and the times we eat
25:35 actually matter in regards to the pattern.
25:37 It matters as far as when we exercise, we know that if you
25:41 exercise in the morning when the cortisol goes up
25:43 you also affect the metabolism, the affect mood
25:46 you affect everything, exercise is not just exercise,
25:48 it's the best mood altering drug out there.
25:52 It's the best sleep-inducing drug out there.
25:55 It's the best metabolic stimulant, especially if it's
26:00 done early, so our system is based on clocks.
26:03 Have you ever done Double Dutch jump rope?
26:06 Yes! Really? Were you good at it?
26:10 Because I picture the body and having this Double Dutch
26:12 right, and it's just like you said, the circadian rhythm
26:16 but a lot of times we live in such a way that its
26:19 outside of that rhythm, it's like conflicting and so we don't
26:25 experience that flourishing life you know that it
26:29 feels like you are doing double-Dutch well like
26:31 ah, I'm in the groove, I got the rhythm and I'm syncing
26:34 with the ropes and I think sometimes, well if we learned
26:37 how to live more harmoniously with our own biological
26:41 rhythm it would feel like that.
26:42 Are you good at double-Dutch?
26:45 It's hard, I had forgotten how hard it was,
26:48 people who do double-Dutch are so impressive,
26:51 they definitely have rhythm.
26:53 The good news is we don't have to be good at double-Dutch
26:57 to live in rhythm, we can live more harmoniously with our own
27:01 biological rhythm and it's going to be amazing.
27:05 It's what you were made for.


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Revised 2025-01-21